BMBF "Prev OP" (under construction)
Within the PrevOP research network "Preventing the progression of primary Osteoarthritis by high impact long-term physical exercise regimen - key mechanisms, efficacy, and long-term results" the aim of our sub-project is to assess and to quantitatively analyze morphological and structural changes in cartilage with respect to different levels of exercise by means of high-frequency quantitative ultrasound. We hypothesize that that morphology and structure of cartilage as well as the progression of osteoarthritis can be quantitatively assessed non-invasively with ultrasound. The proposed work program is focused on monitoring and analysis of changes in cartilage volume, shape, and quality – based on different but combined medical imaging modalities – and its relation to existing OA scores.
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